Prader-Willi syndrome

Also referred to as PWS, Prader-Willi syndrome is an extremely rare genetic disorder that causes obesity, shortness in height, and intellectual disability. There are fewer than 20,000 cases of PWS in the United States each year.

PWS is caused by a genetic change in chromosome 15, where in 70% of instances, it comes from a deletion of the gene deriving from the father. This is also called paternal deletion. The odds of this condition occurring in a child is very unlikely, so the odds of a family having multiple children with PWS is almost zero. 

Typically beginning around the age of 2 is a constant desire to eat due to never feeling full, otherwise known as hyperphagia. This is typically the most prevalent difficulty for individuals with PWS, as it typically causes obesity. In addition, individuals with PWS have an IQ that is below average, although it varies from individual to individual with the condition. Here are some myths regarding PWS.

Myths

Myth 1: Obesity is the only sign of PWS

In additon to an increased likelihood of obesity, there are other physical characteristics that are prevelent, such as weaked bone tissue, light skin and hair, etc.

Myth 2: There is no treatment for PWS.

Treatments include early intrviention and physical and speech therapies.

Individuals with PWS may also be induced with a short stature, eye problems, teeth problems (such as grinding and soft enamel), sleep apnea, scoliosis, osteoporosis (weakened bones), and other complications. PWS also includes underdeveloped genitalia and onset puberty in both males and females with the condition.